Nebraska is increasingly facing significant nitrogen (N) management challenges in sustaining corn production while protecting drinking groundwater quality. The “4Rs” of nutrient stewardship (application of nutrients from the Right source, at the Right place, in the Right time and at Right rate) is a promising concept to achieve increased crop production, increased profitability, enhanced environmental protection and improved sustainability. This project seeks to update the UNL Nitrogen (N) recommendation by investigating the potential for achieving higher corn yield and profits while reducing N losses with the Right source (Anhydrous, UAN, ESN, Urea) and Right placement (broadcast, injected) at the Right time (pre-plant, split) of N application. Results of this study and other relevant studies will be used to improve UNL’s nitrogen algorithm and conduct an economic analysis to assess the return on investment of the “4Rs” and the “cost” of reducing nitrogen losses.